Understanding splicing regulation through RNA splicing maps
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چکیده
منابع مشابه
Understanding splicing regulation through RNA splicing maps
Alternative splicing is a highly regulated process that greatly increases the proteome diversity and plays an important role in cellular differentiation and disease. Interactions between RNA-binding proteins (RBPs) and pre-mRNA are the principle regulator of splicing decisions. Findings from recent genome-wide studies of protein-RNA interactions have been combined with assays of the global effe...
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ژورنال
عنوان ژورنال: Trends in Genetics
سال: 2011
ISSN: 0168-9525
DOI: 10.1016/j.tig.2010.12.001